Clara Syrup (Loratadine 5 mg / 5 mL) is an oral pediatric antihistamine formulation designed to manage and relieve symptoms associated with allergic rhinitis and chronic idiopathic urticaria (hives). Formulated specifically for pediatric administration, this liquid syrup provides targeted symptomatic relief from upper respiratory allergies without causing significant drowsiness.
Medical Indications & Clinical Benefits
Clara Syrup acts directly on histamine receptors to attenuate allergic responses triggered by environmental allergens, including pollen, dust mites, pet dander, and mold spores.
Allergic Rhinitis Symptom Management: Helps alleviate sneezing, rhinorrhea (runny nose), nasal itching, and mucosal congestion.
Ocular Allergy Relief: Reduces allergic conjunctivitis symptoms, such as watery, red, and itchy eyes.
Dermatological Allergy Relief: Indicated for chronic idiopathic urticaria, effectively reducing pruritus (itching), skin redness, and the formation of hives or wheals.
24-Hour Symptom Control: Maintains steady therapeutic plasma levels to provide continuous, all-day relief with a single daily dose.
Pediatric-Friendly Formulation: Liquid presentation ensures accurate volumetric dosing for children who have difficulty swallowing solid oral dosage forms (tablets).
Active Ingredient & Mechanism of Action
Active Ingredient
Loratadine: 5 mg per 5 mL of syrup.
Mechanism of Action
Loratadine is a long-acting, non-sedating second-generation H1-receptor antagonist.
Selective Binding: Loratadine selectively binds to peripheral H1 receptors on effector cells, blocking histamine from binding to its target sites during an allergic reaction.
Minimal Central Nervous System (CNS) Penetration: Unlike first-generation antihistamines, loratadine exhibits minimal crossing of the blood-brain barrier. Consequently, it does not readily bind to cerebral H1 receptors, substantially reducing the incidence of sedation, drowsiness, or cognitive impairment.
Anti-Inflammatory Properties: In addition to its antihistaminic effect, loratadine demonstrates mild suppression of inflammatory mediator release from mast cells and basophils.
Dosage & Administration Guidelines
For precise dosing, always use the calibrated measuring cup or spoon provided with the package.
Age Group,Weight Range,Recommended Dosage,Frequency
Children 2 to 12 Years,Body weight > 30 kg,10 mL (10 mg),Once daily
Children 2 to 12 Years,Body weight ≤ 30 kg,5 mL (5 mg),Once daily
Adults & Children Over 12 Years,N/A,10 mL (10 mg),Once daily
Storage & Handling Instructions
Store below 25°C in a dry place.
Keep the bottle tightly closed in its original carton to protect from light.
Keep out of reach and sight of children.
Do not use after the expiration date printed on the bottle and outer package.
Medication
