Avalon Avoban 2% Nasal Ointment 3G

Avalon Avoban 2% Nasal Ointment (3g) is a targeted prescription topical antibacterial agent formulated specifically for intranasal administration. Containing mupirocin calcium 2% w/w (equivalent to 20 mg mupirocin per gram), this formulation is clinically indicated for the eradication of nasal colonization by susceptible Gram-positive bacteria, particularly Staphylococcus aureus, including Methicillin-Resistant Staphylococcus aureus (MRSA) strains.

The nasal passages frequently serve as a primary reservoir for staphylococcal bacteria. Decolonization of the anterior nares helps reduce the risk of autoinfection and cross-transmission in clinical and community settings, particularly prior to surgical interventions or in institutional healthcare environments.

Active Ingredient

Active Substance

• Mupirocin Calcium 2% w/w

Inactive Ingredients & Base

The product utilizes a soft, white-to-off-white paraffin-based ointment vehicle specifically designed to maintain stability in the mucous membranes of the nasal passages without causing significant mucosal dryness.

Clinical Indications 

• Eradication of Nasal Staphylococcal Colonization: Effective against susceptible strains of Staphylococcus aureus harbored in the anterior nares.

• MRSA Decolonization Regimens: Used under professional medical supervision as part of infection control protocols to clear Methicillin-Resistant Staphylococcus aureus carriage in high-risk individuals or healthcare workers.

• Pre-Operative Prophylaxis: Applied in specific clinical protocols to reduce the incidence of surgical site infections (SSIs) caused by endogenous nasal carriage of S. aureus.

Dosage & Administration

Avoban 2% Nasal Ointment is a prescription medication and must be administered strictly according to a qualified healthcare practitioner's instructions.

Standard Application Protocol

1. Hand Hygiene: Thoroughly wash hands with soap and water before and after application.

2. Dosing: Apply a small, matchhead-sized amount (approximately 30 mg) of ointment onto a clean cotton swab or the tip of the pinky finger.

3. Application: Insert the ointment into the inner surface of each anterior nostril (naris).

4. Distribution: Press the nostrils together and gently massage the sides of the nose for 10–15 seconds to ensure uniform distribution of the ointment throughout the nasal vestibule.

5. Frequency & Duration: Typically applied twice daily for 5 to 7 days, or as dictated by local clinical guidelines and sensitivity testing. Do not exceed the prescribed duration to prevent the development of bacterial resistance.

Safety Precautions, Side Effects & Contraindications

Contraindications

• Known hypersensitivity or allergic reaction to mupirocin, mupirocin salts, or any component of the ointment vehicle.

Adverse Reactions

Avoban 2% Nasal Ointment is generally well tolerated when applied to the nasal mucosa. Infrequent localized adverse effects may include:

• Mild, transient nasal burning or stinging upon application.

• Localized mucosal dryness, irritation, or itching.

• Mild rhinorrhea (runny nose) or congestion.

Clinical Warnings & Precautions

• Ophthalmic Safety: Avoid contact with the eyes. If accidental contact occurs, rinse thoroughly with cool water.

• Systemic Absorption: Minimal systemic absorption occurs following topical nasal administration on intact mucous membranes.

• Overgrowth of Non-Susceptible Organisms: Prolonged or repeated usage may result in the overgrowth of non-susceptible organisms, including fungi. Discontinue use if bacterial resistance or severe local irritation develops.

• Pregnancy & Lactation: Use during pregnancy or breastfeeding only if clearly indicated and prescribed by a physician following a risk-benefit evaluation.

Product Specifications