Procto-Glyvenol Cream is a multi-component topical pharmacological agent clinically indicated for the local symptomatic management of internal and external hemorrhoids. This targeted rectal formulation combines a local anesthetic with a synthetic venotonic agent. It provides immediate, localized relief from the acute inflammatory discomfort, pruritus (itching), burning sensations, and pain associated with hemorrhoidal disease and anal fissures.
Key Medical Benefits & Clinical Value
1. Multi-Symptomatic Relief of Anorectal Discomfort
Hemorrhoidal flare-ups manifest through localized vascular inflammation, causing severe discomfort during bowel movements and prolonged sitting. Procto-Glyvenol exerts a rapid calming effect on the perianal skin and rectal mucosa, neutralizing intense itching and burning sensations by stabilizing local nerve endings.
2. Reduction of Local Vascular Inflammation and Edema
The formulation works at the circulatory level to target the primary cause of hemorrhoids: swollen, distended rectal veins. By reducing capillary permeability and strengthening the vascular walls, the cream decreases localized swelling (edema), promotes tissue recovery, and reduces the risk of minor rectal bleeding caused by friction.
3. Suitable for Both Internal and External Pathologies
The inclusion of a specialized, smooth-tip rectal applicator enables precise, hygienic delivery of the cream above the dentate line for internal hemorrhoids, while the smooth emollient base allows for non-irritating manual application to external perianal lesions.
Ingredients & Mechanism of Action
Core Active Formulation (Per 100g of Cream)
Tribenoside (5.0g): A synthetic venotonic compound that acts locally to reduce vascular permeability, inhibit pro-inflammatory substances, and increase the muscle tone of small blood vessels.
Lidocaine Hydrochloride (2.0g): A potent, fast-acting local anesthetic of the amide class that temporarily blocks voltage-gated sodium channels along pain-sensing nerve fibers.
Mode of Action:
Nerve Blockade: Lidocaine prevents the generation and conduction of pain signals from the inflamed perianal area, delivering rapid, localized numbness without systemic sedative effects.
Vascular Stabilization: Tribenoside actively counters chronic venous congestion. It works as an antagonist against specific endogenous inflammatory mediators (such as histamine and bradykinin) that cause blood vessel dilation and tissue swelling. This helps ease the strain on the affected anorectal venous plexuses.
Usage Instructions & Safety Precautions
Clinical Administration Guidelines
For optimal therapeutic results and infection control, patients must strictly adhere to the following medical protocol:
Pre-Application Hygiene: Thoroughly cleanse the perianal region with mild, unscented soap and warm water. Gently pat dry with a clean towel before application.
External Hemorrhoids: Apply a small, pea-sized amount of cream to the affected external area using a clean fingertip up to twice daily (morning and evening) until acute symptoms subside.
Internal Hemorrhoids: Wash hands thoroughly. Screw the enclosed plastic applicator nozzle onto the 30gm tube. Gently insert the lubricated applicator tip into the anal canal and squeeze the tube lightly to deposit the cream internally.
Post-Application Sanitization: Remove the applicator nozzle after each use, clean it thoroughly with warm running water and soap, dry it completely, and replace the protective cap onto the tube. Wash hands immediately after administration.
Maintenance Phase: Once acute symptoms decrease, the frequency of application may be reduced to once daily, preferably before retiring for sleep.
Crucial Safety Precautions
Contraindications: Do not use if you have a documented hypersensitivity to tribenoside, lidocaine, other amide-type local anesthetics, or any of the excipients within the cream.
Special Populations: Pregnant women (particularly during the first trimester) and lactating mothers must consult their managing physician before starting Procto-Glyvenol therapy to weigh potential clinical benefits against embryonic risks.
Duration of Treatment: If symptoms do not improve within 7 to 10 days of continuous use, or if severe rectal bleeding occurs, stop usage immediately and seek an urgent consultation with a gastroenterologist or proctologist.
Storage Parameters: Store the tube tightly closed at temperatures below 30°C. Protect from excessive heat, do not freeze, and keep out of the sight and reach of children.
Brands
